Dr. Daniela Begolo

Evaluation of early stage opportunities in healthcare for VC investments

Evaluation of early stage opportunities in healthcare for VC investments

Mode of action analysis and effect on RNA processing of a new benzoxaborole compound series in the eukaryotic parasite Trypanosoma brucei. In addition to skills previously acquired, set up of mRNA transcription and trans-splicing assays in T. brucei; contributions to set up CRISPR/Cas system in the lab. Compliance to pharmaceutical company standards; contribution to integrate new employees within the team; student supervision and mentorship

Drug mode of action studies for small molecules target identification in the eukaryotic parasite Trypanosoma brucei. Drugs handling and EC50 measurements; T. brucei cell culture (BSL 2 lab); cloning techniques; molecular biology assays; cell biology assays; MiSeq sequencing, data analysis; metabolomics, data analysis Community development; public speaking; frequent traveling; work and time organization, independent project planning; student supervision

Advanced molecular biology, organic and bioorganic chemistry, nanotechnologies, structural biology, immunological techniques, industrial production

Cell and molecular biology, biological and biotechnological techniques, chemistry, immunology and pathology, bioinformatics, patents, bioethics