Sophie Brusseau

• Coordinate compound microtiter plate preparation campaigns • Optimize infrastructure within compound logistics facility • Design of high quality compound distribution workflows • Management of compound bioprofiling activities • First contact for sourcing of compounds from academic groups • Management of academic and commercial compound registrations • Oversee quality control analytics of compound solutions

Leading the method development and assay automation of IVD immuno-purification pre-analytical techniques using liquid handler instruments. Design and qualification of a new assay platform, working in collaboration with QA, Marketing and Regulatory departments. Creation and management of SOP, qualification and training documentation. Providing technical expertise to customer support and application department, training and support to international customers. Carrying out risk analyses (FMEA)

Performed long term stability study on drug candidates including formulation studies and pH screening. Outsourcing testing to CRO. Performed antibody screening and characterisation using chromatographic methods and DLS. Developed DSC and chromatographic methodologies to achieve comprehensive characterisation of antigens, Fcabs and mAb2.

Analytical testing on drug substances and drug products according to cGMP/GLP and SOPs, including HPLC, DLS, SDS-PAGE, osmolality testing. Completed troubleshooting and out-of-specification investigations. Performed long term stability study on drug candidates including formulation studies and pH screening. Outsourced testing to CRO.

Principles of Medical Diagnosis, Screening and Monitoring. Experimental Design and Methodology. Bioinformatics. Advanced Diagnostic Technologies. Principles of Design and Production in the Diagnostics Industry. Translational Medicine. Economics, Ethics and Legislation Affecting Medical Diagnostics

Analytical Instrumentation, Process Engineering, Molecular Biology, Microbiology, Immunology, Project Management, Marketing, Quality.

Biology, Physiology, Biochemistry, Molecular Biology, Pharmacology, Microbiology, Immunology and Physics.