Dr. Boris Krichel

"Dynamics of viral structures - Uetrecht Group" -Manage lab and team @ Uni Siegen -Establish TopDown proteomics workflows for endogenous viral proteins -Native TopDown mass spectrometry of antibodies and protein complexes -Supervise graduate students in lab project and thesis writing -Establish laser lab and modify mass spectrometers for hydroxyl labelling and UV dissociation

• Research top-down MS of coronaviral nsp-RNA complexes, native MS of small molecule inhibitor binding to viral enzymes • Plan and implement gene technology approvals for group-wide S1 and S2 research projects • Supervise PhD, Master and Bachelor students • Set up protein production and mass spectrometry labs for Q-ToF, Q-Exactive UHMR and timsToF • Repair and maintain LC and MS systems and communicate with MS vendor companies • Coordinate sample preparation and operate DESY synchrotron beamtime experiments

-Mass spectrometry and structural biology of coronaviral proteins -RNA-protein binding -Established MS and Biochemistry research lab -PhD representative