Dr. Maksim Zakhartsev
Angestellt, Senior Researcher, Norwegian University of Life Sciences
Ås, Norwegen
Werdegang
Berufserfahrung von Maksim Zakhartsev
Bis heute 7 Jahre und 6 Monate, seit Jan. 2017
Senior Researcher
Norwegian University of Life Sciences
Reconstruction of whole-genome metabolic model of Atlantic salmon Salmo salar. The goal of the project is optimisation of the fish growth by means of diet for application in salmon farming • network reconstruction • Flux Balance Analysis • integration of high-throughput experimental data • model parameterization. The model aims to optimize a whole range of possible diets of farmed salmon. Gut microbiota will receive particular attention.
1 Jahr, Jan. 2016 - Dez. 2016
Freelancer
Center of Systems Biology, University of Stuttgart
2 Jahre, Jan. 2014 - Dez. 2015
post-doc
University of Hohenheim, Stuttgart, Germany
Optimization of large-scale proteomics using Orbitrap MS analyser Q Exactive Plus (ThermoScientific) • Arabidopsis kinome: exploration of possibilities for modeling of plant signaling pathways • Dynamic interactome of the H+-ATPase: phosphoproteomics / PPI • SCX and RP HPLC of peptides • UltraHPLC (Easy nLC, ThermoScientific) • sample preparation • data analysis in MaxQuant • peptide library construction
5 Monate, Jan. 2013 - Mai 2013
Visiting Researcher
Max Planck Institute for Biochemistry
MS centric aproach in shotgun proteomics using LC-MS/MS: deep proteomics • Orbitrap MS analyser Q Exactive (ThermoScientific) • SCX and RP HPLC of peptides • UltraHPLC (Easy nLC, ThermoScientific) • sample preparation • data analysis in MaxQuant • peptide library construction
1 Jahr, Jan. 2012 - Dez. 2012
Freelancer
Center of Systems Biology, University of Stuttgart
Research area: dynamic modeling of yeast central carbon metabolism
1 Jahr und 10 Monate, März 2010 - Dez. 2011
post-doc
University of Heidelberg
Institute of Pharmacy and Molecular Biotechnology (IPMB). MedSys project “Drug based induction of pluripotent human stem cells derived from human somatic cells”: drug discovery • screening assay development • target identification • mathematical modeling • Teaching: Metabolic Engineering • practical courses on Biochemistry and Bioanalytics
2 Jahre und 8 Monate, Juli 2007 - Feb. 2010
post-doc
Universuity of Stuttgart
Institut für Bioverfahrenstechnik (IBVT). SysMO project “Microorganism Systems Biology: energy and Saccharomyces cerevisiae”: dynamic modeling of metabolic network • fermentation • perturbation experiments • robotized metabolomics • bioanalytics (GS-MS, HPLC) • network reconstruction • metabolic flux balance analysis • model parameterization
1 Jahr, Juli 2006 - Juni 2007
post-doc
AWI
Project “Metabolic compensation of temperature effect in yeast central metabolism”: metabolic adaptation • fermentation • metabolomics • NMR • cellular energy metabolism • modeling
3 Jahre, Juni 2003 - Mai 2006
Docent
Jacobs University (Bremen)
Department of Biochemical Engineering. Research area: yeast metabolic engineering • directed protein evolution • HTS • assay development • bioanalytics • downstream processes • protein purification • biothermodynamics • whole genome microarray analysis • high throughput platform technologies/devices • mass spectrometry Teaching: biochemistry • metabolic engineering • high throughput screening technologies • practical courses • seminars
Ausbildung von Maksim Zakhartsev
4 Jahre und 6 Monate, Dez. 1998 - Mai 2003
Biochemistry
University of Antwerp (Belgium)
Physiological and molecular adaptation of ectotherms to temperature
3 Jahre und 3 Monate, Jan. 1995 - März 1998
Comparative Biochemistry
Institute of Marine Biology (RAS, Vladivostok, Russia)
Comparative Biochemistry, Adaptational Biochemistry of marine organisms
4 Jahre und 10 Monate, Sep. 1987 - Juni 1992
Analytical Biochemistry
Far Eastern State University (Vladivostok, Russia)
chromatography, lipidology, adaptational biochemistry
Sprachen
Englisch
Fließend
Russisch
Muttersprache
Deutsch
Grundlagen